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Vitamin D, vitamin D binding protein gene polymorphisms, race and risk of incident stroke: the Atherosclerosis Risk in Communities (ARIC) study.

Andrea L C SchneiderP L LutseyE SelvinT H MosleyA R SharrettK A CarsonW S PostJ S PankowA R FolsomR F GottesmanE D Michos
Published in: European journal of neurology (2015)
Low 25(OH)D is a risk factor for stroke. Persons with low 25(OH)D who are genetically predisposed to high DBP (rs7041 G, rs4588 A alleles), who therefore have lower predicted bioavailable 25(OH)D, may be at greater risk for stroke, although our results were not conclusive and should be interpreted as hypothesis generating.
Keyphrases
  • atrial fibrillation
  • binding protein
  • cardiovascular disease
  • brain injury
  • blood brain barrier