The Role of Preoperative Chemotherapy in the Management of Synchronous Resectable Colorectal Liver Metastases: A Meta-Analysis.

Kostas TepelenisGeorgios Pappas-GogosPanagiotis NtellasKonstantinos E Tsimogiannis Aikaterini DadouliDavide MauriGeorgios K Glantzounis

Published in: Current oncology (Toronto, Ont.) (2023)

Preoperative chemotherapy should be suggested in patients with high disease burden. The number of cycles of preoperative chemotherapy should be low (3-4) to avoid increased postoperative morbidity. However more prospective studies are needed to clarify the exact role of preoperative chemotherapy in patients with synchronous resectable colorectal liver metastases.

Keyphrases

liver metastases
locally advanced
patients undergoing
rectal cancer
squamous cell carcinoma
radiation therapy
molecular dynamics