Determinants of death in critically ill COVID-19 patients during the first wave of COVID-19: a multicenter study in Brazil.
Fernando Wagner da Silva RamosFernanda Chohfi AtallahMaria Aparecida de SouzaElaine Maria FerreiraFlávia Ribeiro MachadoFlavio Geraldo Resende de FreitasPublished in: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia (2022)
In this study, most of our cohort required invasive mechanical ventilation and almost one third had HAIs, which were independently associated with a higher risk of death. Other factors related to death were Charlson Comorbidity Index, SOFA score at admission, and clinical complications during ICU stay. Nosocomial COVID-19 infection was not associated with death. The main immediate causes of death were refractory shock and multiple organ dysfunction syndrome.