Real-life utility of five-gene panel test in preoperative thyroid fine-needle aspiration biopsy: a large cohort of 740 patients study.

Jiajia TangJiaojiao MaXuehua XiLiangkai WangHuilin LiShirui HuoBo Zhang

Published in: Endocrine (2022)

The mutation frequency of the five-gene panel is 72.3% in thyroid FNAs. BRAF.p.V600E has the highest alteration rate, which is closely associated with tumor size and cytological results. The five-gene panel can improve the sensitivity and accuracy of FNA cytology, which may represent a valid adjunct technique in distinguishing thyroid nodules.

Keyphrases

fine needle aspiration
ultrasound guided
copy number
end stage renal disease
genome wide
genome wide identification
newly diagnosed
chronic kidney disease
gene expression
patients undergoing
peritoneal dialysis
dna methylation
genome wide analysis
patient reported