Clonal Hematopoiesis in Young Women Treated for Breast Cancer.

Christopher J Gibson Geoffrey G Fell Tal Sella Adam S Sperling Craig Snow Shoshana M Rosenberg Gregory Kirkner Ashka Patel Deborah A Dillon Alexander G Bick Donna S Neuberg Ann H Partridge Peter Grant Miller

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)

Our data show that for young women with early-stage breast cancer, CHIP is uncommon after cytotoxic exposure, is unlikely to contribute to adverse outcomes over the decade-long follow up and may not require additional monitoring if discovered incidentally.

Keyphrases

early stage
big data
high throughput
circulating tumor cells
squamous cell carcinoma
deep learning
sentinel lymph node
breast cancer risk