Nocturnal hypoxemia severity and renin-angiotensin system activity in obstructive sleep apnea.

Ann A ZaluckyDavid D M NichollPatrick J HanlyMarc J PoulinTanvir C TurinShahebina WaljiGeorge B HandleyJill K RaneriDarlene Y SolaSofia B Ahmed

Published in: American journal of respiratory and critical care medicine (2016)

The severity of nocturnal hypoxemia influences the magnitude of renal, but not the systemic, RAS activation independently of obesity in patients with OSA.

Keyphrases

obstructive sleep apnea
positive airway pressure
sleep apnea
insulin resistance
metabolic syndrome
weight loss
type diabetes
blood pressure
weight gain
high fat diet induced
adipose tissue
physical activity
depressive symptoms