Dynamic changes in longitudinal circulating tumour DNA profile during metastatic colorectal cancer treatment.

Sheehyun KimYoojoo LimJun-Kyu KangHwang-Phill KimHanseong RohSu Yeon KimDongin LeeDuhee BangSeung-Yong JeongKyu Joo ParkSae-Won HanTae-You Kim

Published in: British journal of cancer (2022)

ctDNA profile provided a more accurate landscape of tumour and dynamic changes compared to radiological evaluation. Longitudinal ctDNA monitoring may improve personalised treatment decision-making.

Keyphrases

circulating tumor
metastatic colorectal cancer
decision making
single cell
mass spectrometry
combination therapy
replacement therapy