VEGF synthesis is induced by prostacyclin and TGF-β in distal lung fibroblasts from COPD patients and control subjects: Implications for pulmonary vascular remodelling.
Gunilla Westergren-ThorssonMariam BagherAnnika Andersson-SjölandLena ThimanClaes-Göran LöfdahlOskar HallgrenLeif BjermerAnna-Karin Larsson-CallerfeltPublished in: Respirology (Carlton, Vic.) (2017)
VEGF is synthesized in high amounts by distal lung fibroblasts and may have a crucial role in ongoing vascular remodelling processes in the distal lung compartments.
Keyphrases
- minimally invasive
- end stage renal disease
- vascular endothelial growth factor
- endothelial cells
- newly diagnosed
- ejection fraction
- chronic kidney disease
- chronic obstructive pulmonary disease
- extracellular matrix
- peritoneal dialysis
- pulmonary hypertension
- transforming growth factor
- patient reported outcomes
- epithelial mesenchymal transition
- air pollution
- signaling pathway