Childhood Obesity and Congenital Heart Disease: A Lifelong Struggle.
Giovanni di SalvoIrene CattapanJennifer FumanelliAlice PozzaSara MoscatelliJolanda SabatinoMartina AvesaniElena ReffoDomenico SiricoBiagio CastaldiAlessia CeruttiRoberta BiffantiValeria PergolaPublished in: Journal of clinical medicine (2023)
Congenital heart disease (CHD) affects approximately one in every one hundred infants worldwide, making it one of the most prevalent birth abnormalities globally. Despite advances in medical technology and treatment choices, CHD remains a significant health issue and necessitates specialized care throughout an individual's life. Childhood obesity has emerged as a novel global epidemic, becoming a major public health issue, particularly in individuals with lifelong conditions such as CHD. Obesity has profound effects on cardiac hemodynamics and morphology, emphasizing the importance of addressing obesity as a significant risk factor for cardiovascular health. Obesity-induced alterations in cardiac function can have significant implications for cardiovascular health and may contribute to the increased risk of heart-related complications in obese individuals. Moreover, while diastolic dysfunction may be less apparent in obese children compared to adults, certain parameters do indicate changes in early left ventricular relaxation, suggesting that obesity can cause cardiac dysfunction even in pediatric populations. As most children with CHD now survive into adulthood, there is also concern about environmental and behavioral health risk factors in this particular patient group. Addressing obesity in individuals with CHD is essential to optimize their cardiovascular health and overall quality of life. This review aims to succinctly present the data on the impact of obesity on CHD and to enhance awareness of this perilous association among patients, families, and healthcare providers.
Keyphrases
- weight loss
- metabolic syndrome
- congenital heart disease
- healthcare
- insulin resistance
- public health
- left ventricular
- type diabetes
- high fat diet induced
- weight gain
- risk factors
- adipose tissue
- bariatric surgery
- heart failure
- young adults
- magnetic resonance imaging
- risk assessment
- acute coronary syndrome
- physical activity
- computed tomography
- pain management
- transcatheter aortic valve replacement
- body mass index
- quality improvement
- climate change
- coronary artery disease
- atrial fibrillation
- percutaneous coronary intervention
- hypertrophic cardiomyopathy
- human health
- health insurance
- preterm birth
- diffusion weighted imaging