The Role and Activation Mechanism of TAZ in Hierarchical Microgroove/Nanopore Topography-Mediated Regulation of Stem Cell Differentiation.
Penghui HuQian GaoHuimin ZhengYujuan TianGuoying ZhengXiaoyu YaoJunjiang ZhangXudong WuLei Sui
Published in: International journal of nanomedicine (2021)
Our results demonstrated that actin cytoskeletal polymerization and MAPK signaling pathway activation triggered by SLM-AHT surface were essential for TAZ activation, which played a dominant role in SLM-AHT surface-induced stem cell fate decision.