Evaluation of bone metastatic burden by bone SPECT/CT in metastatic prostate cancer patients: defining threshold value for total bone uptake and assessment in radium-223 treated patients.
Takuro UmedaMitsuru KoizumiShohei FukaiNoriaki MiyajiKazuki MotegiShuto NakazawaTomohiro TakiguchiPublished in: Annals of nuclear medicine (2017)
We established a threshold value (SUV > 7.0) for three-dimensional TBU for evaluating active bone metastatic burden in prostate cancer patients using bone SPECT/CT. Despite the small number of patients, we expect the change in TBU could be more accurate and sensitive than the change in BSI among patients who received Ra-223.
Keyphrases
- prostate cancer
- end stage renal disease
- newly diagnosed
- ejection fraction
- bone mineral density
- chronic kidney disease
- small cell lung cancer
- squamous cell carcinoma
- prognostic factors
- peritoneal dialysis
- rheumatoid arthritis
- patient reported outcomes
- magnetic resonance imaging
- soft tissue
- high resolution
- postmenopausal women
- bone loss
- bone regeneration
- body composition
- ankylosing spondylitis
- clinical evaluation