Adolescent oligodendrogenesis and myelination restrict experience-dependent neuronal plasticity in adult visual cortex.
Wendy XinMegumi KanekoRichard H RothAlbert ZhangSonia NoceraJun B DingMichael P StrykerJonah R ChanPublished in: bioRxiv : the preprint server for biology (2023)
These results demonstrate a critical role for oligodendrocytes in shaping the maturation and stabilization of cortical circuits and support the concept of myelin acting as a brake on neuronal plasticity during development.