SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy.
Irene Lo CignoFederica CalatiCarlo GironeCinzia BorgognaAldo VenutiRenzo L BoldoriniMarisa GariglioPublished in: British journal of cancer (2023)
Our findings uncover an essential role of SIRT1 in HPV-driven oncogenesis, which may have direct translational implications for the treatment of this type of cancer.