Comparison of large-scale deletions of the sperm mitochondrial DNA in normozoospermic and asthenoteratozoospermic men.
Maryam GholinezhadYousefreza Yousefnia-PashaAbasalt Hosseinzadeh ColagarMilad Mohammadoo-KhorasaniAli BidmeshkipourPublished in: Journal of cellular biochemistry (2018)
Our findings suggested that these large-scale deletions of mtDNA may be genetic risk factors for poor sperm quality in asthenoteratozoospermia-induced male infertility. Thus, it is necessary to understand the mechanisms behind the generation of these deletions.