Th17/Treg imbalance in COPD progression: A temporal analysis using a CS-induced model.

Juliana Tiyaki ItoDaniela Aparecida de Brito CervilhaJuliana Dias LourençoNatália Gomes GonçalvesRildo Aparecido VolpiniElia Garcia CaldiniGilles LandmanChin Jia LinAna Paula Pereira VelosaWalcy Paganelli Rosolia TeodoroIolanda de Fátima Lopes Calvo TibérioThais MauadMilton de Arruda MartinsMariangela MacchioneFernanda Degobbi Tenorio Quirino Dos Santos Lopes

Published in: PloS one (2019)

Our results showed that the microenvironmental stimuli produced by the release of cytokines during COPD progression lead to a Th17/Treg imbalance.

Keyphrases

chronic obstructive pulmonary disease
lung function
high glucose
diabetic rats
cystic fibrosis
air pollution
endothelial cells