Incidence and Types of Cardiac Arrhythmias in the Peri-Ictal Period in Patients Having a Generalized Convulsive Seizure.
Laura VilellaChristina Y MiyakeChaitanya GanneJohnson P HampsonShirin Jamal OmidiManuela Ochoa-UrreaBlanca TalaveraOscar ManceraNorma J HuppJaison S HampsonM R Sandhya RaniNuria LacueyShiqiang TaoRup K SainjuDaniel FriedmanMaromi NeiCatherine A ScottBrian K GehlbachStephan U SchueleJennifer A OgrenRonald M HarperBeate DiehlLisa M BatemanOrrin DevinskyGeorge B RichersonGuo-Qiang ZhangSamden D LhatooPublished in: Neurology (2024)
Markers of seizure severity are not related to seizure-induced arrhythmias of interest, suggesting that other factors such as occult cardiac abnormalities may be relevant for their occurrence. Seizure-induced ESAWB and bradycardia were more frequent in SUDEP cases, although this observation was based on a very limited number of SUDEP patients. Further case-control studies are needed to evaluate the yield of arrhythmias of interest along with respiratory changes as potential SUDEP biomarkers.