Contributions of Interleukin-33 and TSLP in a papain-soaked contact lens-induced mouse conjunctival inflammation model.

Jobu SugitaYosuke AsadaWaka IshidaSatoshi IwamotoKatsuko SudoHajime SutoToru MatsunagaKen FukudaAtsuki FukushimaNorihiko YokoiTatsukuni OhnoMiyuki AzumaNobuyuki EbiharaHirohisa SaitoMasato KuboSusumu NakaeAkira Matsuda

Published in: Immunity, inflammation and disease (2017)

Innate immunity-driven type 2 immune responses of the ocular surface are dependent on IL-33, TSLP, basophils, and ILC2. These components may be possible therapeutic targets for refractory allergic keratoconjunctivitis.

Keyphrases

immune response
oxidative stress
diabetic rats
high glucose
drug induced
toll like receptor
inflammatory response
cataract surgery
stress induced