Causal association pathways between fetuin-A and kidney function: a mediation analysis.

Philip Etabee BasseyPawin NumthavajSasivimol RattanasiriPiyamitr SritaraMark McEvoyBoonsong OngphiphadhanakulAmmarin Thakkinstian

Published in: The Journal of international medical research (2022)

Our study revealed a possible role of fetuin-A in the etiology of declining renal function through mediating body mass index, uric acid, diabetes mellitus, and hypertension via complex causal pathways. Further studies to clarify these mediated effects are recommended.

Keyphrases

uric acid
body mass index
metabolic syndrome
blood pressure
physical activity
weight gain
single cell
adipose tissue
skeletal muscle