MiR-106a targets ATG7 to inhibit autophagy and angiogenesis after myocardial infarction.

Guofeng BaiJinghao YangWeili LiaoXiaofeng ZhouYingting HeNian LiLiuhong ZhangYifei WangXiaoli DongHao ZhangJinchun PanLiangxue LaiXiaolong YuanXilong Wang

Published in: Animal models and experimental medicine (2024)

Our results indicate that miR-106a may inhibit autophagy and angiogenesis by targeting ATG7. This mechanism may be a potential therapeutic treatment for MI.

Keyphrases

cell proliferation
long non coding rna
cell death
endothelial cells
long noncoding rna
endoplasmic reticulum stress
vascular endothelial growth factor
signaling pathway
oxidative stress
combination therapy
smoking cessation