Outcomes of Childhood Noninfant Acute Lymphoblastic Leukemia With 11q23/ KMT2A Rearrangements in a Modern Therapy Era: A Retrospective International Study.

Andishe AttarbaschiAnja MörickeChristine J HarrisonGeorg MannAndre Baruchel Barbara De Moerloose Valentino ConterMeenakshi DevidasSarah ElitzurGabriele EscherichStephen P Hunger Keizo HoribeAtsushi ManabeMignon L Loh Rob Pieters Kjeld SchmiegelowLewis B SilvermanJan Stary Ajay Vora Ching-Hong PuiMartin SchrappeMartin Zimmermann

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2022)

-rearranged ALL has improved, but allo-HSCT failed to affect outcome. Targeted therapies are needed to reduce relapse and treatment-related mortality rates.

Keyphrases

acute lymphoblastic leukemia
cardiovascular events
allogeneic hematopoietic stem cell transplantation
risk factors
stem cells
cardiovascular disease
metabolic syndrome
young adults
hematopoietic stem cell
insulin resistance
bone marrow
cell therapy
glycemic control