Nonalcoholic Fatty Liver Disease, Liver Fibrosis and Utility of Noninvasive Scores in Patients with Acromegaly.

İmdat Eroğlu Burcin Gonul Iremli İlkay Sedakat İdilman Deniz Yuce İncilay Lay Deniz Akata Tomris Erbas

Published in: The Journal of clinical endocrinology and metabolism (2023)

Active acromegaly may protect from NAFLD due to high GH. In acromegalic patients, NAFLD risk cannot be explained with classical risk factors, hence additional risk factors must be identified. TyG is the best score to evaluate NAFLD risk. Lower ANGPTL-8 in acromegalic patients with NAFLD implies this hormone may be raised due to insulin resistance rather than being a cause for NAFLD.

Keyphrases

risk factors
liver fibrosis
insulin resistance
end stage renal disease
ejection fraction
newly diagnosed
growth hormone
type diabetes
adipose tissue
metabolic syndrome
prognostic factors
high fat diet
patient reported