High-Fat Diet Alters Acylcarnitine Metabolism of the Retina and Retinal Pigment Epithelium/Choroidal Tissues in Laser-Induced Choroidal Neovascularization Rat Models.

Pinghui WeiMeiqin HeYing WangGuoge Han

Published in: Molecular nutrition & food research (2023)

HFD hastens choroidal neovascularization. The study comprehensively documented acylcarnitine profiles in a CNV rat model. Acylcarnitine's odd-even and carbon-chain length properties may guide future therapeutics.

Keyphrases

high fat diet
optical coherence tomography
diabetic retinopathy
optic nerve
insulin resistance
adipose tissue
age related macular degeneration
vascular endothelial growth factor
gene expression
oxidative stress
small molecule
type diabetes
metabolic syndrome
current status
skeletal muscle
endothelial cells