How much do molecular shapes matter?

Published in: Acta crystallographica Section B, Structural science, crystal engineering and materials (2023)

Nifedipine (NIF) molecules (L-type calcium channel antagonists) pack in solvated structures showing strikingly similar patterns [see Jones et al. [(2023). Acta Cryst. B79, https://doi.org/10.1107/S2052520623001282]. How much do molecular shapes, such as the NIF molecule which resembles the letter T, matter in their associations in crystals?

Keyphrases

high resolution
mass spectrometry