Impact of Clinical and Morphological Factors on Long-Term Mortality in Patients with Myocardial Bridge.
György BárcziDávid BeckerNóra SydóZoltan RuszaHajnalka VágóAttila OláhBéla MerkelyPublished in: Journal of cardiovascular development and disease (2022)
Although myocardial bridging (MB) has been intensively investigated using different methods, the effect of bridge morphology on long-term outcome is still doubtful. We aimed at describing the anatomical differences in coronary angiography between symptomatic and non-symptomatic LAD myocardial bridges and to investigate the influence of clinical and morphological factors on long-term mortality. In our retrospective, long-term, single center study we found relevant MB on the left anterior descendent (LAD) coronary artery in 146 cases during a two-year period, when 11,385 patients underwent coronary angiography due to angina pectoris. Patients were divided into two groups: those with myocardial bridge only (LAD-MB neg , n = 78) and those with associated obstructive coronary artery disease (LAD-MB pos , n = 68). Clinical factors, morphology of bridge by quantitative coronary analysis and ten-year long mortality data were collected. The LAD-MB neg group was associated with younger age and decreased incidence of diabetes mellitus, as well as with increased minimal diameter to reference diameter ratio (LAD-MB neg 54.5 (13.1)% vs. LAD-MB pos 46.5 (16.4)%, p = 0.016), while there was a tendency towards longer lesions and higher vessel diameter values compared to the LAD-MB pos group. The LAD-MB pos group was associated with increased mortality compared to the LAD-MB neg group. The analysis of our data showed that morphological parameters of LAD bridge did not influence long-term mortality, either in the overall population or in the LAD-MB neg patients. Morphological parameters of LAD bridge did not influence long-term mortality outcomes; therefore, it suggests that anatomical differences might not predict long-term outcomes and should not influence therapy.
Keyphrases
- coronary artery disease
- coronary artery
- cardiovascular events
- newly diagnosed
- risk factors
- left ventricular
- prognostic factors
- stem cells
- patient reported outcomes
- heart failure
- adipose tissue
- metabolic syndrome
- percutaneous coronary intervention
- mass spectrometry
- bone marrow
- artificial intelligence
- coronary artery bypass grafting
- pulmonary arterial hypertension