Anticoagulation Control in Older Atrial Fibrillation Patients Receiving Vitamin K Antagonist Therapy for Stroke Prevention.
Hanis Hanum ZulkiflyGregory Yoke Hong LipDeirdre A LanePublished in: International journal of clinical practice (2022)
Suboptimal (TTR and PINRR <70%) anticoagulation control was evident in all patients. Risk of bleeding increased, but there was no difference in thromboembolic events and all-cause mortality in those aged ≥80 years. Improving TTR to ≥70% and enhancing anticoagulation monitoring of VKA use remain a clinical priority to prevent bleeding complications, particularly among those aged 80 years and above.
Keyphrases
- atrial fibrillation
- oral anticoagulants
- left atrial
- catheter ablation
- left atrial appendage
- direct oral anticoagulants
- end stage renal disease
- heart failure
- ejection fraction
- percutaneous coronary intervention
- newly diagnosed
- chronic kidney disease
- peritoneal dialysis
- venous thromboembolism
- prognostic factors
- risk factors
- acute coronary syndrome
- mitral valve
- blood brain barrier
- brain injury
- subarachnoid hemorrhage