Cancer Type and Histology Influence Cutaneous Immunotherapy Toxicities: A Multi-Institutional Cohort Study.

Guihong WanSara KhattabBonnie W LeungShijia ZhangNga NguyenMatthew TranChuck LinCrystal T ChangNora AlexanderRuple JairathJordan PhillippsKimberly TangAhmad RajehLeyre ZubiriSteven T ChenShadmehr DemehriKun-Hsing YuAlexander GusevShawn G KwatraNicole R LeBoeufKerry L ReynoldsYevgeniy R Semenov

Published in: The British journal of dermatology (2024)

The highest rate of cirAEs and subsequent survival benefits were observed in cutaneous malignancies treated with ICIs. This study improves our understanding of patients who are at highest risk of developing cirAEs and would, therefore, benefit from appropriate counseling and closer monitoring by their oncologists and dermatologists throughout their ICI therapy. Limitations include its retrospective nature and cohort from one geography.

Keyphrases

newly diagnosed
end stage renal disease
ejection fraction
prognostic factors
papillary thyroid
mesenchymal stem cells
squamous cell
hiv testing
men who have sex with men
lymph node metastasis
skin cancer