Diabetic striatopathy in type 1 diabetes mellitus: a rare conundrum.
Vijayakumar KarthikPuthiyaveetil Khadar JabbarAbilash NairShameer BasheerPublished in: BMJ case reports (2023)
Diabetic striatopathy is a clinicoradiological syndrome characterised by acute hyperkinetic movement disorder in the form of hemichorea-hemiballism with basal ganglia abnormalities in neuroimaging. The hallmark basal ganglia abnormalities appear as hyperdensities in CT brain and hyperintensities in MRI brain, which could mislead the clinician towards an erroneous diagnosis of cerebral haemorrhage. It is classically described in elderly patients with type 2 diabetes mellitus, and its occurrence in type 1 diabetes is extremely rare. This case report entails the clinical details of a young man in his 20s with type 1 diabetes mellitus who had uncontrolled blood glucose levels and presented with a recent onset of abnormal movements in his left upper and lower limbs. The semiology, biochemistry and radiological investigation findings and treatment are detailed. A clear understanding of the condition could lead to an early diagnosis, spare the patient unnecessary investigations and improve treatment outcomes.
Keyphrases
- case report
- type diabetes
- blood glucose
- glycemic control
- resting state
- contrast enhanced
- white matter
- cerebral ischemia
- magnetic resonance imaging
- wound healing
- liver failure
- functional connectivity
- subarachnoid hemorrhage
- risk assessment
- computed tomography
- cardiovascular disease
- blood pressure
- drug induced
- respiratory failure
- insulin resistance
- multiple sclerosis
- positron emission tomography
- brain injury
- adipose tissue
- diffusion weighted imaging
- acute respiratory distress syndrome