Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis.

Tao Wang Yan-Bin Gao Rongchuan YueXiaolei WangYimin ShiJiayi XuBingjie WuYimeng Li

Published in: Evidence-based complementary and alternative medicine : eCAM (2020)

Ginsenoside Rg1 protects podocytes from hyperlipidemia-induced damage by inhibiting pyroptosis through the mTOR/NF-κB/NLRP3 axis, indicating a potential therapeutic function in DN.

Keyphrases

high glucose
signaling pathway
nlrp inflammasome
oxidative stress
endothelial cells
lps induced
high fat diet
pi k akt
cell proliferation
diabetic rats
diabetic nephropathy
nuclear factor
inflammatory response
cancer therapy
high fat diet induced
adipose tissue
insulin resistance
drug induced