Haemodynamic and prognostic associations of liver fibrosis scores in Fontan-associated liver disease.
Irene Martín de MiguelPatrick S KamathAlexander C EgbeYogesh N V ReddyFrank CettaHeidi M ConnollyWilliam R MirandaPublished in: Heart (British Cardiac Society) (2022)
APRI and FIB-4 scores were associated with long-term all-cause mortality in Fontan patients independent of other prognostic markers. Correlations between haemodynamic status and liver scores were weak; furthermore, most markers of liver fibrosis failed to correlate with non-invasive indices, underscoring the complexity of FALD.