Tacrolimus and Cyclosporin Pharmacotherapy, Detection Methods, Cytochrome P450 Enzymes after Heart Transplantation.

Published in: Cardiovascular & hematological agents in medicinal chemistry (2023)

Polypharmacy based on tacrolimus or cyclosporine needs vigilant therapeutic drug monitoring due to the cytochrome P450 enzymes associated with biochemical variables in metabolic pathways. Further attention to polypharmacy should be given to circulate drugs that could hide pharmacokinetics interactions associated with infections, malignancies, chronic kidney disease, and rejection after organ transplantation.

Keyphrases

chronic kidney disease
end stage renal disease
working memory
adverse drug
loop mediated isothermal amplification
smoking cessation
cell therapy
emergency department