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Association of Pace of Aging Measured by Blood-Based DNA Methylation With Age-Related Cognitive Impairment and Dementia.

Karen SugdenAnnchen R KnodtMaxwell L ElliottKyle J BourassaKartik ChamartiDavid L CorcoranAhmad R HaririRenate M HoutsMeeraj KothariStephen B KritchevskyGeorge A KuchelJonathan S MillBenjamin S WilliamsDaniel W BelskyTerrie E Moffittnull null
Published in: Neurology (2022)
Third-generation blood-based DNA methylation measures of aging could prove valuable for measuring differences between individuals in the rate at which they age and in their risk for cognitive decline, and for evaluating interventions to slow aging.
Keyphrases
  • cognitive decline
  • dna methylation
  • mild cognitive impairment
  • cognitive impairment
  • genome wide
  • gene expression
  • physical activity
  • copy number