Metabolic Modulation and Potential Biomarkers of the Prognosis Identification for Severe Aortic Stenosis after TAVR by a Metabolomics Study.

Yanbiao Liao Chang Liu Tianyuan Xiong Mingyue Zhao Wen Zheng Yuan Feng Yi-Jian Li Yuanweixiang Ou Zhengang Zhao Yong Peng Jiafu Wei Qiao Li Wei Meng Xiaojing Liu Mao Chen

Published in: Cardiology research and practice (2020)

This is the first study to reveal systemic and cardiac metabolites changed significantly in patients with AS after TAVR. Some altered metabolites involved in the arginine and proline metabolism pathway in the peripheral vein could predict left ventricle regression, which merited further study.

Keyphrases

aortic stenosis
transcatheter aortic valve replacement
aortic valve
left ventricular
ejection fraction
aortic valve replacement
mass spectrometry
heart failure
atrial fibrillation
gene expression
coronary artery
pulmonary hypertension
early onset
genome wide