Spatial transcriptomics reveals heterogeneity of histological subtypes between lepidic and acinar lung adenocarcinoma.
Linshan XieHui KongJinjie YuMengting SunShaohua LuYong ZhangJie HuFang DuQiuyu LianHongyi XinJian ZhouXiangdong WangCharles A PowellFred R HirschChunxue BaiYuanlin SongJun YinDa-Wei YangPublished in: Clinical and translational medicine (2024)
These findings illustrate that assessing patient histological subtypes at the single-cell level is feasible. Additionally, tumour endothelial cells that express PD-L1 in stage IA LUAD suppress immune-responsive CD8+ T cells.