New-Onset Salt-and-Pepper Skin Changes Associated With Vaccination and Trauma in Systemic Sclerosis: Immunity Matters.

In the recent issue of The Journal of Rheumatology , Chung et al 1 reported the associations of perifollicular hypopigmentation with disease subtypes and organ involvement in a systemic sclerosis (SSc) cohort in the United States. Perifollicular hypopigmentation, also termed salt-and-pepper appearance , is a typical manifestation in SSc.