Genome-wide DNA methylation pattern in systemic sclerosis microvascular endothelial cells: Identification of epigenetically affected key genes and pathways.

Shadia NadaBashar KahalehNezam Ibrahim Altorok

Published in: Journal of scleroderma and related disorders (2021)

Our data suggest the presence of significant genome-wide DNA methylation aberrancies in systemic sclerosis microvascular endothelial cells, and identify novel affected genes and pathways in systemic sclerosis microvascular endothelial cells.

Keyphrases

systemic sclerosis
genome wide
endothelial cells
dna methylation
interstitial lung disease
high glucose
copy number
gene expression
bioinformatics analysis
electronic health record
big data
transcription factor
artificial intelligence