Application of immunocapture and nanoflow LC-MS/MS to overcome the barriers to the quantitation of oxytocin in plasma of women in third stage labour.

Sebastiaan BijttebierTri-Hung NguyenMichelle P McIntoshCarl M J KirkpatrickBart RemmerieLieve DillenPete Lambert

Published in: British journal of clinical pharmacology (2024)

The presented IP-nLC-MS/MS method succeeded in overcoming the sensitivity challenge related to the assay of OT in TSL plasma and thereby revealing the PK profiles of OT in TSL plasma clinical study samples.

Keyphrases

ms ms
liquid chromatography tandem mass spectrometry
high throughput
type diabetes
metabolic syndrome
pregnant women
pregnancy outcomes
insulin resistance