Digital image analysis of intraepithelial B-lymphocytes to assess lymphoepithelial lesions in salivary glands of Sjögren's syndrome patients.

Martha S van GinkelTineke van der SluisMarian L C BulthuisHenk J BuikemaErlin A HaackeSuzanne ArendsStine HarderFred K L SpijkervetHendrika BootsmaArjan VissinkFrans G M KroeseBert van der Vegt

Published in: Rheumatology (Oxford, England) (2022)

Intraepithelial B-lymphocytes are a specific finding in salivary gland biopsies of pSS patients and can be used as an objective alternative to LEL scoring. Therefore, identification of B-lymphocyte containing ducts should be added to the diagnostic histopathological work-up of patients suspected of pSS.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
rheumatoid arthritis
patient reported outcomes