Patterns of rpoC Mutations in Drug-Resistant Mycobacterium tuberculosis Isolated from Patients in South Korea.
Yeo Jun YunJong Seok LeeJe Chul YooEunjin ChoDahee ParkYoon Hoh KookKeun Hwa LeePublished in: Tuberculosis and respiratory diseases (2018)
Fifteen different types of mutations were identified and were predominantly single-nucleotide substitutions (91.7%). Mutations were found only in dual isoniazid- and RFP-resistant isolates of M. tuberculosis. No mutations were identified in any of the drug-susceptible strains.