Identification of zinc finger MIZ-type containing 2 as an oncoprotein enhancing NAD-dependent protein deacetylase sirtuin-1 deacetylase activity to regulate Wnt and Hippo pathways in non-small-cell lung cancer.

Xueting GanYuheng FengYang LiuXuyong LinXinmiao YuXuezhu RongXu-Yong Lin

Published in: Cellular & molecular biology letters (2024)

ZMIZ2 promotes the malignant phenotype of lung cancer by regulating Wnt/Hippo pathways through SIRT1, providing an experimental basis for discovering novel biomarkers and developing tumor-targeted drugs.

Keyphrases

cell proliferation
stem cells
oxidative stress
cancer therapy
ischemia reperfusion injury
amino acid
drug delivery
bioinformatics analysis
oxide nanoparticles