Contemporary rates and predictors of fast progression of chronic kidney disease in adults with and without diabetes mellitus.
Alan S GoJingrong YangThida C TanClaudia S CabreraBergur V StefanssonPeter J GreasleyJuan D Ordoneznull nullPublished in: BMC nephrology (2018)
In a large, contemporary population of adults with eGFR 30-59 ml/min/1.73 m2, accelerated progression of kidney dysfunction within 2 years affected ~ 1 in 4 patients with diabetes and ~ 1 in 7 without diabetes. Regardless of diabetes status, the strongest independent predictors of fast CKD progression included proteinuria, elevated systolic blood pressure, heart failure and anemia.
Keyphrases
- chronic kidney disease
- blood pressure
- heart failure
- end stage renal disease
- type diabetes
- glycemic control
- cardiovascular disease
- left ventricular
- small cell lung cancer
- epidermal growth factor receptor
- oxidative stress
- heart rate
- tyrosine kinase
- hypertensive patients
- acute heart failure
- adipose tissue
- insulin resistance