The integrative bioinformatic analysis deciphers the predicted molecular target gene and pathway from curcumin derivative CCA-1.1 against triple-negative breast cancer (TNBC).

Dhania NovitasariRiris Istighfari JenieJun-Ya KatoEdy Meiyanto

Published in: Journal of the Egyptian National Cancer Institute (2021)

We suggested CCA-1.1 possibly regulated cell cycle process during mitosis, which led to cell death. These findings needed to be investigated through experimental studies to reinforce scientific data of CCA-1.1 therapy against TNBC.

Keyphrases

cell cycle
cell death
cell proliferation
electronic health record
transcription factor
genome wide
copy number
atomic force microscopy
case control
cell cycle arrest
bone marrow
deep learning
signaling pathway
network analysis
replacement therapy
cell therapy
high speed
genome wide analysis