The plasma membrane calcium ATPase 4 does not influence parasite levels but partially promotes experimental cerebral malaria during murine blood stage malaria.
Ana Villegas-MendezNicholas StaffordMichael J HaleyNormalita Eka PravitasariFlorence BaudoinAdnan AliPuji Budi Setia AsihJosephine E SiregarEsther BaenaDin SyafruddinKevin N CouperDelvac OceandyPublished in: Malaria journal (2021)
The finding suggests that PMCA4 may play a minor role in the development of severe malarial complications, but that this appears independent of direct effects on parasite invasion, growth or survival within RBCs.