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The Endometrial Stem/Progenitor Cells and Their Niches.

Baolan SunXi ChengQiang Wu
Published in: Stem cell reviews and reports (2024)
Endometrial stem/progenitor cells are a type of stem cells with the ability to self-renew and differentiate into multiple cell types. They exist in the endometrium and form niches with their neighbor cells and extracellular matrix. The interaction between endometrial stem/progenitor cells and niches plays an important role in maintaining, repairing, and regenerating the endometrial structure and function. This review will discuss the characteristics and functions of endometrial stem/progenitor cells and their niches, the mechanisms of their interaction, and their roles in endometrial regeneration and diseases. Finally, the prospects for their applications will also be explored.
Keyphrases
  • stem cells
  • endometrial cancer
  • extracellular matrix
  • cell therapy
  • induced apoptosis
  • single cell
  • oxidative stress
  • current status