Antithrombotic Therapy in Elderly Patients with Acute Coronary Syndromes.
Clara BonanadFrancisca Esteve ClaramuntSergio Garcia-BlasAna AyestaPablo Díez-VillanuevaJosé Ángel Pérez-RiveraJosé Luis FerreiroJoaquim CánovesFrancisco López-FornásAlbert Ariza SoléSergio RaposeriasDavid VivasRegina BlancoDaznia Bompart BerroteránAlberto Cordero-FortJulio NunezLorenzo FácilaIván J Núñez-GilJose Luis Gorriz TeruelVicente BodíManuel Martinez-SellésJuan Miguel Ruiz-NodarFrancisco Javier ChorroPublished in: Journal of clinical medicine (2022)
The treatment of acute coronary syndrome (ACS) in elderly patients continues to be a challenge because of the characteS.G.B.ristics of this population and the lack of data and specific recommendations. This review summarizes the current evidence about critical points of oral antithrombotic therapy in elderly patients. To this end, we discuss the peculiarities and differences reported referring to dual antiplatelet therapy (DAPT) in ACS management in elderly patients and what might be the best option considering these population characteristics. Furthermore, we analyze antithrombotic strategies in patients with atrial fibrillation (AF), with a particular focus on those cases that also present coronary artery disease (CAD). It is imperative to deepen our knowledge regarding the management of these challenging patients through real-world data and specifically designed geriatric studies to help resolve the questions remaining in their disease management.
Keyphrases
- acute coronary syndrome
- antiplatelet therapy
- percutaneous coronary intervention
- coronary artery disease
- atrial fibrillation
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- electronic health record
- coronary artery bypass grafting
- heart failure
- peritoneal dialysis
- prognostic factors
- stem cells
- artificial intelligence
- clinical practice
- bone marrow
- data analysis
- hip fracture
- case control