Multiomic analysis reveals decidual-specific transcriptional programing of MAIT cells.

Jessica VazquezMelina ChavarriaDeborah A ChasmanRene Welch SchwartzChanel T TylerGladys LopezRachel C FisherIrene M OngAleksandar K Stanic

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2021)

MAIT cells are present in the decidua basalis and obtain a unique gene expression profile. The presence of MR1 on APCs coupled with in vitro activation by E.coli suggests that MAIT cells might be involved in tissue-repair mechanisms at the maternal-fetal interface.

Keyphrases

induced apoptosis
cell cycle arrest
gene expression
endoplasmic reticulum stress
signaling pathway
magnetic resonance
cell death
pregnant women
transcription factor
heat shock
weight gain
pregnancy outcomes