Occupational exposure to asphalt mixture during road paving is related to increased mitochondria DNA copy number: a cross-sectional study.
Yiyi XuChristian H LindhBo A G JönssonKarin BrobergMaria AlbinPublished in: Environmental health : a global access science source (2018)
Road asphalt paving in open areas resulted in PAHs exposure, as shown by elevation of PAH metabolites in urine. Asphalt workers may experience oxidative stress, evidenced by alternation in mtDNAcn; however the effects could not be fully explained by exposure to PAHs from the asphalt mixture.
Keyphrases
- copy number
- polycyclic aromatic hydrocarbons
- mitochondrial dna
- oxidative stress
- heavy metals
- genome wide
- health risk assessment
- minimally invasive
- human health
- physical activity
- dna methylation
- ms ms
- dna damage
- circulating tumor
- cell free
- ischemia reperfusion injury
- risk assessment
- risk factors
- gene expression
- reactive oxygen species
- endoplasmic reticulum
- climate change
- signaling pathway
- nucleic acid