Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries.
Meng ZhangHeng AnFeng-Shi ZhangHaoran JiangTeng WanYongqiang WenNa HanPeixun ZhangPublished in: International journal of molecular sciences (2023)
Peripheral nerve injuries are common neurological disorders, and the available treatment options, such as conservative management and surgical repair, often yield limited results. However, there is growing interest in the potential of using chitosan-based biopolymers as a novel therapeutic approach to treating these injuries. Chitosan-based biopolymers possess unique characteristics, including biocompatibility, biodegradability, and the ability to stimulate cell proliferation, making them highly suitable for repairing nerve defects and promoting nerve regeneration and functional recovery. Furthermore, these biopolymers can be utilized in drug delivery systems to control the release of therapeutic agents and facilitate the growth of nerve cells. This comprehensive review focuses on the latest advancements in utilizing chitosan-based biopolymers for peripheral nerve regeneration. By harnessing the potential of chitosan-based biopolymers, we can pave the way for innovative treatment strategies that significantly improve the outcomes of peripheral nerve injury repair, offering renewed hope and better prospects for patients in need.
Keyphrases
- peripheral nerve
- drug delivery
- wound healing
- cell proliferation
- stem cells
- hyaluronic acid
- end stage renal disease
- induced apoptosis
- chronic kidney disease
- current status
- metabolic syndrome
- adipose tissue
- human health
- risk assessment
- machine learning
- cell cycle
- endoplasmic reticulum stress
- big data
- brain injury
- blood brain barrier
- replacement therapy
- cerebral ischemia