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Deficiency and altered phenotype of mucosal-associated invariant T cells in systemic sclerosis.

Manon Lesturgie-TalarekVirginie GonzalezLucie BeaudoinCamelia FrantzNoémie SénotZouriatou GoudaCamille RousseauJérôme AvouacAgnès LehuenYannick Allanore
Published in: Journal of scleroderma and related disorders (2023)
Circulating mucosal-associated invariant T cells were reduced and exhibited an activated phenotype in systemic sclerosis patients. This peripheral mucosal-associated invariant T cell deficiency may be related to enhanced apoptosis and/or homing in inflamed tissue, particularly in systemic sclerosis-interstitial lung disease patients.
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