Trend of HPV 16/18 Genotypes in Cervical Intraepithelial Neoplasia Grade 3: Data for 2007-2018.

Luca GiannellaGiovanni Delli CarpiniJacopo Di GiuseppeGiorgio BoganiBarbara GardellaErmelinda MontiCarlo Antonio LiveraniAlessandro GhelardiSalvatore InsingaMichele MontanariFrancesco RaspagliesiArsenio SpinilloPaolo VercelliniElena RoncellaAndrea Ciavattini

Published in: Infection and drug resistance (2021)

The prevalence of CIN3 lesions related to HPV 16/18 genotypes decreased over time from 2007 to 2018. These data highlight a herd effect of the HPV vaccine. However, fifteen years after HPV vaccine introduction, we are still a long way from herd immunity. The increase in high-risk types 31/33/45/52/58 will need to be reassessed when the nonavalent vaccine impact will be more reliable.

Keyphrases

high grade
electronic health record
cervical cancer screening
big data
data analysis
artificial intelligence