Cardiovascular Safety of Metoclopramide Compared to Domperidone: A Population-Based Cohort Study.
Andrea C CowanAmit X GargEric McArthurFlory Muanda TsoboMatthew A WeirPublished in: Journal of the Canadian Association of Gastroenterology (2020)
The 30-day risk for a hospital encounter with ventricular arrhythmia was low for both metoclopramide and domperidone, with no significant difference in the rate between the two drugs. The higher 30-day risk of death observed with metoclopramide compared with domperidone in this study has also been observed in other studies and warrants further investigation.